Mengxia Li Selected Research

Endonucleases

3/2021	APE1 may influence CD4+ naïve T cells on recurrence free survival in early stage NSCLC.
12/2020	A randomized, double-blind, placebo-controlled study of B-cell lymphoma 2 homology 3 mimetic gossypol combined with docetaxel and cisplatin for advanced non-small cell lung cancer with high expression of apurinic/apyrimidinic endonuclease 1.
5/2018	miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic/apyrimidinic endonuclease.
1/2018	The regulatory role of APE1 in epithelial-to-mesenchymal transition and in determining EGFR-TKI responsiveness in non-small-cell lung cancer.
10/2017	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.
11/2016	Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients.
10/2015	Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-dependent manner in human osteosarcoma.
12/2014	Signal-on electrochemical immunoassay for APE1 using ionic liquid doped Au nanoparticle/graphene as a nanocarrier and alkaline phosphatase as enhancer.
2/2014	Apurinic/apyrimidinic endonuclease 1 induced upregulation of fibroblast growth factor 2 and its receptor 3 induces angiogenesis in human osteosarcoma cells.
1/2014	Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma.

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Mengxia Li Research Topics

Disease

33	Neoplasms (Cancer) 02/2022 - 10/2011
13	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2020 - 01/2013
5	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2013
5	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 02/2014
4	Hypertension (High Blood Pressure) 01/2022 - 05/2006
4	Inflammation (Inflammations) 01/2022 - 12/2016
4	Obesity 01/2020 - 10/2005
4	Adenocarcinoma of Lung 01/2020 - 01/2013
4	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 01/2013
3	Ischemic Stroke 12/2022 - 01/2021
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 05/2006
3	Lung Neoplasms (Lung Cancer) 11/2020 - 01/2013
3	Choriocarcinoma 01/2020 - 11/2018
3	Critical Illness (Critically Ill) 12/2015 - 03/2014
2	Esophageal Squamous Cell Carcinoma 02/2022 - 01/2022
2	Pre-Eclampsia (Preeclampsia) 01/2022 - 12/2018
2	Infections 10/2021 - 06/2013
2	COVID-19 08/2021 - 01/2021
2	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2021 - 01/2020
2	B-Cell Lymphoma (Lymphoma, B Cell) 12/2020 - 01/2014
2	Glucose Intolerance 01/2020 - 04/2016
2	Genomic Instability 10/2017 - 05/2014
2	Body Weight (Weight, Body) 04/2016 - 12/2015
2	Ataxia Telangiectasia (Louis Bar Syndrome) 11/2014 - 12/2012
2	Multiple Myeloma 01/2014 - 01/2014
2	Atherosclerosis 05/2006 - 10/2005
1	Central Nervous System Diseases (CNS Diseases) 12/2022
1	Proteinuria 01/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 03/2021
1	Coronary Disease (Coronary Heart Disease) 01/2021
1	Disease Progression 01/2021
1	Wilms Tumor (Wilm's Tumor) 01/2021
1	Dyspnea (Shortness of Breath) 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2021

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 03/2021 - 10/2011
14	EndonucleasesIBA 03/2021 - 01/2013
7	PlatinumIBA 01/2022 - 10/2014
7	DNA (Deoxyribonucleic Acid)IBA 12/2014 - 04/2011
6	LipidsIBA 01/2022 - 10/2005
5	Cisplatin (Platino)FDA LinkGeneric 12/2020 - 01/2014
4	RNA (Ribonucleic Acid)IBA 02/2022 - 02/2014
4	Chondroitin Sulfates (Chondroitin Sulfate)IBA 08/2020 - 01/2018
4	Peptides (Polypeptides)IBA 08/2020 - 11/2018
4	Pharmaceutical PreparationsIBA 01/2020 - 01/2014
4	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 07/2015
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2013
3	MicroRNAs (MicroRNA)IBA 01/2020 - 10/2017
3	GlucansIBA 01/2019 - 12/2016
3	Small Interfering RNA (siRNA)IBA 10/2015 - 01/2013
3	DNA-Activated Protein KinaseIBA 11/2014 - 04/2011
3	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 11/2014 - 04/2011
2	Biological ProductsIBA 12/2022 - 08/2020
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2019
2	Matrix Metalloproteinases (MMPs)IBA 03/2021 - 08/2020
2	Blood Glucose (Blood Sugar)IBA 01/2021 - 07/2015
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 03/2014
2	Docetaxel (Taxotere)FDA Link 12/2020 - 01/2015
2	GossypolIBA 12/2020 - 01/2014
2	ChitosanIBA 01/2020 - 01/2019
2	Amino Acids FDA Link 01/2020 - 11/2019
2	ProdigiosinIBA 01/2020 - 11/2019
2	ChemokinesIBA 01/2020 - 01/2020
2	Insulin (Novolin)FDA Link 01/2020 - 04/2016
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2019 - 12/2016
2	ErbB Receptors (EGF Receptor)IBA 10/2018 - 07/2018
2	Tyrosine Kinase InhibitorsIBA 10/2018 - 01/2018
2	GenisteinIBA 10/2018 - 09/2015
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2018 - 10/2015
2	gossypol acetic acidIBA 01/2015 - 01/2014
2	matrigelIBA 01/2015 - 02/2014
2	Phosphotransferases (Kinase)IBA 11/2014 - 12/2012
1	Messenger RNA (mRNA)IBA 02/2022
1	6-methyladenineIBA 02/2022
1	N-methyladenosineIBA 02/2022
1	AdipokinesIBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Tyrosine (L-Tyrosine)FDA Link 01/2022
1	toripalimabIBA 01/2022
1	oxidized low density lipoproteinIBA 01/2022
1	InterleukinsIBA 01/2022
1	Complementary DNA (cDNA)IBA 10/2021
1	Indicators and Reagents (Reagents)IBA 03/2021
1	KetonesIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021
1	BilirubinIBA 01/2021
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2021
1	Amifostine (Ethyol)FDA LinkGeneric 01/2021
1	Phospholipases (Phospholipase)IBA 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021

Therapy/Procedure

11	Therapeutics 12/2022 - 10/2011
11	Drug Therapy (Chemotherapy) 01/2022 - 01/2014
6	Radiotherapy 01/2021 - 01/2013
2	Aftercare (After-Treatment) 01/2020 - 12/2014
1	Mesenchymal Stem Cell Transplantation 12/2022
1	Transplantation 12/2022
1	Stem Cell Transplantation 12/2022
1	Critical Care (Surgical Intensive Care) 08/2021
1	Brachytherapy 01/2021